The gene AGAP2-AS1 may have Genomic and Proteomic products available from Sigma-Aldrich.

12, ENSG00000229950, TFAP2A-AS1, 1.70E-15, 8.59E-13, 1.89. 13, ENSG00000138792 246, ENSG00000255737, AGAP2-AS1, 8.44E-10, 1.70E-07, -1.53.

It is becoming now more widely accepted that 3’ antisense lncRNAs can modify the expression of their gene counterparts and we demonstrate here that this is the case as well for the tandem AGAP2 – AGAP2-AS1. AGAP2-AS1 was up-regulated and associated with poor prognosis in GBM. Knockdown of AGAP2 -AS1 suppressed proliferation and invasion, and facilitated apoptosis in GBM cells . To explore the functional relevance of AGAP2AS1 in - GBM cells, we interfered endogenous AGAP2-AS1 expression in U87/MG and U251/MG cells by We also found that AGAP2-AS1 promoted colon cancer cell proliferation, migration and invasion through the Hippo signaling. Conclusion: Upregulated expression of AGAP2-AS1 promoted proliferation, invasion and migration in colon cancer by forming a negative feedback loop with LINC-PINT. EC.5,6 High expression of AGAP2-AS1 has been identiﬁed in gastric cancerandnon-small-celllungcancer,suggestingthatknockdownof AGAP2-AS1 leads to a decrease in cell proliferation and migration, along with the repression of invasion and tumorigenesis.7,8 However, it remains unknown as to whether AGAP2-AS1 inﬂuences cancer progression in EC. Silencing of AGAP2-AS1 was observed to restrain the development of EC both in vitro and in vivo through upregulating miR-195-5p and downregulating FOSL1.

Agap2-as1

Herein, we found that AGAP2-AS1 expression was up-regulated in GBM tissues and cells. High AGAP2-AS1 expression may predict a poor prognosis in GBM patients. The expression of AGAP2-AS1 and miR-16-5p in HCC specimens and cell lines were detected by real-time PCR. The correlation among AGAP2-AS1 and miR-16-5p were disclosed by a dual-luciferase reporter assay, RIP assay and biotin pull-down assay. AGAP2-AS1 is located on chromosome 12q14.1 and consists of 1567 nucleotides. This gene is on a locus with AGAP2 and may function as a co-regulator of AGAP2 [ 8 - 10 ]. The AGAP2-AS1 expression level was significantly upregulated in NSCLC tissues and negatively correlated with poor prognostic outcomes in patients.

2017-02-16

Click the + buttons to view associations for AGAP2-AS1 from the datasets below. If available, associations are ranked by standardized value AGAP2-AS1 dysregulation and characterize the mech-anism by which AGAP2-AS1 regulates its targets in the GC cells.

SP1 induced AGAP2-AS1 plays an important role in tumorigenesis. AGAP2-AS1 knockdown signicantly inhibited proliferation and caused apoptosis in CCA cells. In addition, we demonstrated that AGAP2-AS1 promotes the proliferation of CCA. Conclusions: We conclude that the long non-coding RNA AGAP2-AS1 plays a role in promoting the proliferation of

-8,46 sig. AGAP3. 116988 ArfGAP with GTPase -4.29091, 0.00002, 0.00134, ASMTL-AS1, antisense, 1401769, 1414028, X 0.25865, 0.79591, 0.91497, AGAP2-AS1, antisense, 57726271, 57728356, 12. agap2. januari 2018 – september 2018 9 månader. meru. Instrument panel project AS1 Door panel JFC phase 2.

As shown in Figure 1, the results showed that the me-dian expression level of AGAP2-AS1 was higher in 2016-05-19 Prostate cancer remains a significant cause of cancer-related deaths in male population. More recently, accumulating evidence continues to implicate long non-coding RNAs (lncRNAs), microRNAs (miRNAs), and mRNAs in various types of cancers, including prostate cancer. The current study aimed to elucidate the role of lncRNA AGAP2-AS1/miR-195-5p/PDZ and LIM domain 5 (PDLIM5) in prostate cancer Exploration of Serum Exosomal LncRNA TBILA and AGAP2-AS1 as Promising Biomarkers for Diagnosis of Non-Small Cell Lung Cancer . Yao Tao 1, Yuting Tang 1, Zailin Yang 2, Futao Wu 3, Lu Wang 1, Liyuan Yang 1, Li Lei 1, Yipei Jing 1, Xueke Jiang 1, Hongjun Jin 1, Yao Bai 3, Ling Zhang 1 .
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If available, associations are ranked by standardized value AGAP2-AS1 dysregulation and characterize the mech-anism by which AGAP2-AS1 regulates its targets in the GC cells. Taken together, the obtained findings may provide new insights into the critical role of the lncRNA AGAP2-AS1 in human GC tumorigenesis and progression. Methods Tissue samples and cell lines Fifty paired GC and adjacent nontumor AGAP2‑AS1 were highly expressed in renal tissues. The expression of AGAP2 -AS1 was detected in 539 ccRCC tissues and 72 adjacent healthy tissues using Wilcoxon rank sum test.

Furthermore, knockdown of AGAP2-AS1 significantly inhibited GC cell proliferation, migration, and … AGAP2-AS1 was upregulated in MSC-cultured cells, and knockdown of AGAP2-AS1 reversed the MSC-mediated trastuzumab resistance. Furthermore, MSC culture … 2017-02-16 2019-05-14 2017-02-16 AGAP2-AS1 is Upregulated in NSCLC Tissues To determine whether AGAP2-AS1 is involved in NSCLC tumorigenesis, We determined the ex-pression levels of AGAP2-AS1 in NSCLC tissues and matched normal lung tissues by RT-qPCR. As shown in Figure 1, the results showed that the me-dian expression level of AGAP2-AS1 was higher in 2016-05-19 Prostate cancer remains a significant cause of cancer-related deaths in male population. More recently, accumulating evidence continues to implicate long non-coding RNAs (lncRNAs), microRNAs (miRNAs), and mRNAs in various types of cancers, including prostate cancer.
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AGAP2-AS1 expression was upregulated and associated with poor prognosis of NSCLC. To investigate lncRNA expression levels in NSCLC tissues compared with normal tissues, we first analyzed the

16 AGAP2-AS1 Silencer Select Pre-designed, Validated, and Custom siRNA in Standard, HPLC, and In-vivo Ready Purities. AGAP2-AS1 (≥ 0.6553; n = 56) and those with a low relative expression of AGAP2 AS1 (< 0.6553; n = 54).

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2017-02-16

AGAP2-AS1 expression was upregulated and associated with poor prognosis of NSCLC. To investigate lncRNA expression levels in NSCLC tissues compared with normal tissues, we first analyzed the

27 Mar 2020 LncRNA AGAP2-AS1 (AGAP2 Antisense 1), which is also known as PUNISHER ENSG00000255737, is located at 12q14.1 and has been